New Delhi: Sub-Varian Omicron BA.4 and BA.5, which causes new global surges in infection, including in India, it is better to avoid vaccines and most antibody treatments than the previous variant, said a study published in Nature.
The researchers, led by David D. Ho, Director of the Research Center Aaron Diamond AIDS and Clyde’56 and Helen Wu Professor of Medicine at Columbia University Vagelos College of Physicians and Surgeons, studied the antibody capabilities of individuals who received at least at least an antibody from individuals who receive at least at least receive antibodies from individuals who receive antibodies from individuals who receive antibodies from individuals who receive antibodies from individuals who receive antibodies from individuals who receive at least from individuals who receive at least at least three doses of the MRNA vaccine, or get two shots and then Infected with Omicron, to neutralize the new sub-variant.
This study shows that while BA.2.12.1 is only more resistant than BA.2 in individuals who are vaccinated and encouraged, BA.4 and BA.5 at least four times more resistant than their predecessors.”This virus continues to evolve, as expected, and is not surprising that the new sub-variant that is more transmitted becomes more dominant throughout the world,” said the study.
“Understanding how the current vaccine and antibody care survive with new sub -varians are very important to develop strategies to prevent severe diseases, inpatients, and deaths – if not infection,” Ho said.Scientists also test the ability of 19 monoclonal antibody treatments to neutralize variants and find that only one of the available antibody treatments that remain very effective against this sub-variant.
Subvarian BA.2.12.1, BA.4, and BA.5 quickly developed throughout the world, with BA.4 and BA.5 now forming more than 50 percent of the new COVID-19 cases in the US. This sub-variant is considered more transmitted than the previous Omicron sub-variant, due to some new mutations in surge protein.India has also detected the sub-variant of Omicron BA.4 and BA.5, which is associated with an increase in COVID-19 cases. The two sub-variants were first seen in South Africa in early 2022. So far, BA.5 has been reported in 47 countries and BA.4 in 42 countries.
“Our study shows that because the sub-variant that is very transmitted continues to develop throughout the world, they will cause more breakthrough infections in people who are vaccinated and encouraged with the current mRNA vaccine,” Ho said in this study, that published at this time Tuesday.
Although this study shows that new variants can cause more infections in people who are vaccinated, the vaccine continues to provide reasonable protection against severe diseases, scientists said.Similar results were also obtained by researchers from Göttingen, Germany and their findings were published in June 2022 in Lancet.
Both research groups also tested several antibodies available for treatment.Dr. Rajeev Jayadevan, Co-Chairman National Indian Medical Association (IMA) Covid-19 clusters, said India needed to watch the Omicron sub-variant. “The new variant is fitter and faster to spread, which causes more infections,” he said.